PICO Table

Spring 2026

Rotation PICO/MINI-CAT Question
RT 2 – Pediatrics PICO #1 In children with sickle cell disease presenting with fever, does early empiric broad-spectrum antibiotic administration compared with delayed culture-directed therapy reduce mortality and complications?
RT 2 – Pediatrics PICO #2 In children with acute otitis media, does immediate antibiotic therapy compared with watchful waiting result in faster recovery time?
RT 2 – Pediatrics PICO #3 In children presenting with fever due to a viral illness, how does ibuprofen, compared with acetaminophen, provide faster fever reduction and better symptom relief without increasing adverse effects?
RT 3 – OB/GYN PICO #4 In reproductive-aged women seeking contraception, do long-acting reversible contraceptives (e.g., Nexplanon or IUDs) result in lower unintended pregnancy rates, higher continuation rates, and greater patient satisfaction compared with oral contraceptive pills?
RT 3 – OB/GYN PICO #5 In reproductive-aged women experiencing heavy menstrual bleeding, does treatment with a levonorgestrel-releasing intrauterine device (LNG-IUD) lead to greater reduction in menstrual blood loss, improved quality of life, and lower rates of surgical intervention compared with oral hormonal therapy?
RT 3 – OB/GYN PICO #6 In women with a prior cesarean delivery, how does a trial of labor after cesarean (TOLAC) compare with an elective repeat cesarean section in terms of maternal complications and neonatal outcomes?
RT 4 – LTC Mini-CAT #1 [Pediatrics] In infants, does early introduction of peanut-containing foods compared with delayed or no introduction reduce the development of peanut allergy?

Summer 2026

Rotation PICO/MINI-CAT Question
RT 5 – Ambulatory Care PICO #7 In patients with simple lacerations, does tissue adhesive (e.g., Dermabond) compared to sutures result in similar cosmetic outcomes, infection rates, and patient satisfaction? 
RT 5 – Ambulatory Care PICO #8 In patients with H. pylori infection, does bismuth quadruple therapy (PPI, Bismuth, Tetracycline, Metronidazole) compared to triple therapy (PPI, Clarithromycin, Amoxicillin), achieve higher eradication rates?
RT 5 – Ambulatory Care PICO #9
RT 6 – Emergency Med Mini-CAT #2